What Is Autism? Brain Differences, the Spectrum and Lived Experience
Autism is a lifelong neurodevelopmental difference that can shape sensory processing, communication, social connection, attention, movement, interests and responses to change. It begins in early development, although it may not be recognized until much later.
That definition is accurate but incomplete. In daily life, autism can mean hearing every conversation in a crowded room without being able to filter any out. It can mean calculating social rules that others seem to use automatically. It can mean finding stability, joy or expertise in an interest—and paying a high processing cost when attention must shift.
For one person, autism may be visible through substantial communication and daily-living support needs. For another, the visible signs may be subtle while the private cost appears as exhaustion, masking, shutdown or burnout. Neither experience defines the whole spectrum.
This guide explains the core pattern of autism, what research has found about the brain, what “spectrum” really means, why recognition may happen late, how autism is assessed and what makes life more accessible.
🧭 Autism in One Clear Answer
Autism is not one behaviour, personality type or level of ability. It is a lifelong pattern of development involving two broad clinical areas:
💬 Differences in social communication and interaction
🔁 Restricted or repetitive patterns of behaviour, interests or activity—including sensory differences, a need for sameness and repetitive movement or speech
For a diagnosis, these characteristics must form a broader developmental pattern. None of these traits is enough on its own.
The pattern usually:
🗓️ Has roots in childhood, even when it was not recognized then
🧩 Includes characteristics across multiple areas
🌍 Appears across situations, although its visibility can change
📈 Becomes more or less noticeable as demands and support change
🛠️ Creates meaningful support needs, difficulty or disability in daily life
Autism is not a disease, a parenting failure or a temporary mental-health state. Nor is it automatically a special talent or a harmless difference. It can include valued strengths while also creating serious disability. Both can be true.
If you are looking mainly for recognizable examples, use this guide alongside 25 Signs of Autism in Adults.
🧩 The Core Pattern of Autism
Clinical descriptions divide autism into two domains. In real life, communication, attention, movement, sensory processing, predictability and energy constantly interact.
💬 Social Communication and Interaction
Autistic social processing can differ in conversational timing, nonverbal signals, implied meaning, expectations and relationships.
Possible experiences include:
🗣️ Preferring clear, direct language to hints or implication
⏳ Needing more processing time before responding
👀 Finding that eye contact competes with listening or thinking
🧠 Learning social rules consciously through observation and experience
📚 Giving more detail than other people expect because the detail feels relevant
🔍 Interpreting words accurately but missing an unspoken social message
👥 Finding one-to-one or interest-based interaction easier than unstructured groups
🪫 Needing substantial recovery after apparently successful social contact
These are differences in communication, not an absence of communication or care.
An autistic person may speak fluently, use few spoken words, communicate through an augmentative and alternative communication device, or shift between forms of communication as capacity changes. Spoken language is not a measure of intelligence, empathy or understanding.
Social misunderstandings are also relational. Research on the “double empathy problem” suggests that communication can break down between people who interpret and express experience differently. Autistic people may communicate more comfortably with some other autistic people. Genuine difficulties remain, but not every misunderstanding originates inside the autistic person.
🔁 Repetition, Sameness, Attention and Interests
This domain may involve:
🔁 Repetitive movement, speech, sounds or use of objects
📅 A strong need for predictability, routines or familiar sequences
🌪️ Significant difficulty adapting to unexpected change
🎯 Highly focused interests with unusual intensity, depth or importance
🧠 Deep absorption and difficulty shifting attention
📏 A strong preference for consistency, precision or completing a pattern
🎧 Heightened, reduced or unusual responses to sensory input
Repetitive movement—often called stimming—may regulate attention, emotion, excitement or sensory input. It can include rocking, pacing, finger movements, repeated phrases, humming or touching a familiar texture. Some forms are visible; others are subtle or suppressed.
Routines can reduce the number of unknowns that must be processed at once. A seemingly minor change may require someone to dismantle a detailed mental plan and build a new one under pressure.
Focused interests may provide pleasure, expertise, recovery, identity and connection. The topic need not be unusual; its depth, intensity and role in the person’s life matter more.
Autistic Cognitive Styles explores attention, detail focus and pattern detection in more depth.
🔊 Sensory Processing
Sensory differences are part of the modern diagnostic description of autism and can shape almost every part of daily life. A person may register some input intensely, notice other input less readily or actively seek particular sensations.
This can involve:
🔊 Sound that is painful, startling or impossible to filter
💡 Light, movement or visual clutter that overwhelms concentration
👕 Clothing, touch or temperature that remains intensely present
🍽️ Strong responses to food texture, taste or smell
🌀 Seeking movement, pressure, repetition or strong sensory input
🫀 Difficulty noticing internal signals such as hunger, thirst, pain or the need for the toilet
A person can be hypersensitive in one sensory system and hyposensitive in another. Sensitivity can also change with fatigue, illness, stress, hormonal changes and accumulated load.
When input exceeds available capacity, the result may be pain, confusion, loss of speech, an urgent need to escape, a meltdown or a shutdown. These responses vary and do not prove autism by themselves.
Read The Science of Sensory Processing in Autism for the fuller evidence and mechanisms.
🧠 What Is Actually Different in the Autistic Brain?
Autism is brain-based, but there is no single brain feature shared by every autistic person. Researchers find average differences between groups, not a neat divide between “autistic brains” and “non-autistic brains.” The groups overlap substantially, and the findings vary with age, sex, genetics, language, intellectual ability and the kind of autism represented in a study.
The clearest overall conclusion is not that one brain area is broken. It is that autistic brains can follow different developmental trajectories and coordinate information differently across distributed systems.
🧱 Development, Structure and Growth
Large MRI studies have found small average differences in the development of several areas. These have included parts of the frontal and temporal cortex, the amygdala and structures involved in movement, learning and reward such as the putamen, pallidum and nucleus accumbens.
In a major international study of more than 3,000 autistic and non-autistic people, the autistic group had a slightly thicker frontal cortex, a slightly thinner temporal cortex and small differences in several subcortical structures. The cortical-thickness differences varied across the lifespan and were largest around adolescence.
These are subtle statistical differences, not abnormalities visible in every autistic person. They are too small and too variable to tell whether one individual is autistic. Nor do they show that autistic brains are globally larger, smaller, damaged or “less developed.” Brain development is a changing process, not a single measurement.
🔗 How Brain Networks Communicate
Brain regions work in networks. Functional MRI and EEG examine how their activity is coordinated over time. Autism research has found both stronger and weaker communication within and between networks involved in:
🔊 Sensory and motor processing
🚨 Detecting what is important or urgent
🎯 Directing and switching attention
🧠 Planning and cognitive control
🪞 Self-referential thought and social understanding
⏱️ Combining information arriving at different times
The old claim that autism is simply a condition of “under-connectivity” is not supported. Some autistic people or subgroups show hyperconnectivity in particular networks; others show hypoconnectivity; many show a mixture. The result also depends on age, task and brain region.
These network differences may help explain why a person can detect fine detail yet struggle to combine many signals quickly, focus deeply yet find switching costly, or hear a background sound without the brain automatically downgrading it. They may also affect how speech, facial expression, body language and context are integrated in real time. These are plausible links—not one-to-one explanations for a person’s behaviour.
⚡ Synapses, Signalling and the Balance of Activity
Genes associated with autism often influence synapses—the junctions through which brain cells communicate—as well as ion channels, gene regulation and the brain’s ability to strengthen or weaken connections through experience. Different variants can affect these systems in different directions. “Autistic people have too many brain connections” is therefore an appealing but inaccurate simplification.
Researchers also study the balance between excitatory signalling, which makes neural activity more likely, and inhibitory signalling, which regulates it. Glutamate and GABA are central to this work. A 2024 meta-analysis found lower average GABA concentrations in some autistic groups, especially children and in certain limbic regions. But studies are inconsistent, and there is no evidence of one uniform, brain-wide “chemical imbalance” in every autistic person.
The more defensible conclusion is that the timing and regulation of neural activity may differ in particular regions, developmental stages and autistic subgroups.
🔊 Sensory Filtering, Habituation and Prediction
The brain does not passively record everything around it. It selects what deserves attention, reduces its response to repeated input—a process called habituation—and uses context and past experience to predict what will happen next.
Some autism studies find that sensory responses remain strong for longer, that irrelevant input is suppressed less efficiently or that immediate sensory evidence is weighted differently against prior expectations. This could help explain experiences such as:
🔁 A familiar hum remaining vivid instead of fading into the background
⚡ An unexpected change carrying an unusually high processing cost
🔍 Fine detail being noticed before the overall context becomes clear
🌪️ Several ordinary inputs becoming overwhelming when they must be processed together
These findings do not mean that autistic perception is always “more accurate,” that every autistic person predicts poorly or that one theory explains all of autism. Predictive-processing and habituation models are useful research frameworks, not settled verdicts.
🔬 What Brain Science Cannot Yet Do
There is currently no brain scan, EEG pattern, blood test or chemical measurement that can diagnose autism. Neuroscience cannot look at a scan and reveal a person’s empathy, intelligence, communication ability or support needs.
So what is actually different? On average, autism is associated with differences in developmental timing, the structure of some regions, coordination between brain networks, synaptic biology and the regulation of sensory information. But there are multiple autistic neurobiologies—not one defining autistic brain. Diagnosis still depends on a person’s developmental history and pattern of real-life characteristics, not laboratory imaging.
🌈 What Does “Spectrum” Mean?
The autism spectrum is not a line from “mild” to “severe.” It is a multidimensional profile. Two autistic people can have very different combinations of communication, sensory, cognitive, physical and daily-living needs.
Relevant dimensions can include:
💬 Access to speech and other communication
🧠 Language and information processing
🔊 Sensory sensitivity or sensory seeking
🔄 Starting, stopping and switching tasks
📅 Tolerance of uncertainty and change
🧼 Personal care and daily-living skills
🎯 Attention, interests and learning profile
🫂 Social understanding and relationship needs
🩺 Physical and mental health
🏠 The accessibility of the person’s environment
A person may have exceptional knowledge in one area and need hands-on help in another. Someone may speak confidently when regulated but lose access to speech under overload. Someone who lives independently may still need extensive recovery, planning or practical support.
Support needs change with sleep, pain, illness, stress, demands, sensory load and burnout. A skill available sometimes may not be available reliably, quickly or without cost.
This is why labels such as “high-functioning” and “low-functioning” often conceal more than they explain. The first can minimize serious hidden needs; the second can erase competence, agency and potential. Describing the actual support needed is usually more useful.
🪞 What Autism Can Feel Like From the Inside
Diagnostic criteria describe observable patterns. They often miss the internal work behind them:
Looking away may make it easier to listen.
Repeating a movement may be how the person remains regulated enough to stay.
Talking at length about an interest may be an offer of connection.
Leaving a social event may prevent overload rather than reject the people present.
Not responding immediately may reflect delayed processing rather than defiance.
Deficit-based descriptions can also miss deep absorption, intense enjoyment, detailed perception, pattern recognition, direct communication and strong relationships with interests or values.
These are possibilities, not universal autistic traits. A balanced account does not turn every difficulty into a hidden strength, and it does not require an autistic person to be exceptional in order to deserve acceptance and support.
Explore Autism Strengths and Cognitive Advantages for a careful look at strengths without romanticizing disability.
⚖️ Is Autism a Difference, a Disability or a Disorder?
Clinically, autism spectrum disorder is the diagnostic term used in major classification systems. A diagnosis requires clinically significant difficulty or impairment and can provide access to services, accommodations and legal protection.
The neurodiversity framework understands autism as human neurological variation rather than a disease detached from the person. Many people therefore prefer identity-first language: “autistic person.”
Autism can also be a disability. Some disability arises directly from limited communication, sensory pain, intellectual disability, epilepsy or difficulty with essential activities. Some emerges through inaccessible environments. Often, both matter.
A person does not stop being disabled simply because the environment contributes to the difficulty. And acknowledging disability does not require viewing the person as broken.
Respect means preserving dignity, taking support needs seriously and using the person’s preferred language. Some say “autistic,” others “person with autism,” and some retain “Asperger’s” as part of their identity even though it is no longer a separate diagnosis.
🧬 What Causes Autism?
Autism does not have one single cause.
Research indicates a strong genetic contribution, but there is no single “autism gene.” Many common variants contribute small amounts of likelihood; rarer variants or genetic conditions can have larger effects. Different developmental pathways can lead to autism.
Heritability estimates describe populations. They cannot say how “genetic” one person’s autism is, who “passed it on” or what their future will be.
Research also studies prenatal, perinatal and other developmental factors. Association is not automatically causation, and risk is not blame. Usually, no single event explains why someone is autistic.
What the evidence does support clearly:
❌ Vaccines do not cause autism
❌ Autism is not caused by cold or unresponsive parenting
❌ Autism is not created by screens, diet or a lack of discipline
❌ Trauma does not turn a previously non-autistic person autistic
Trauma, anxiety and depression can coexist with autism and change how it is expressed. They do not cause the underlying developmental pattern.
There is currently no blood test, brain scan or single genetic test that can determine whether someone is autistic. Autism remains a clinical diagnosis based on developmental pattern and present experience.
🌍 How Common Is Autism?
The World Health Organization estimated that about 1 in 127 people globally were autistic in 2021. Other reviews report around 1% or higher where identification is more complete.
Figures vary with diagnostic criteria, records, awareness, services and assessment access. Women, gender-diverse people, some racial or cultural groups, adults and people without intellectual disability have historically been missed more often.
Rising identification does not prove that one new exposure created autism. Broader definitions, improved recognition, diagnostic substitution, service access and public awareness all affect recorded prevalence.
🌱 Why Autism May Be Recognized Only in Adulthood
Autism begins in development. Recognition depends on what others notice, what they expect autism to look like and whether the environment exposes or supports the person’s differences.
An adult may have gone unrecognized because:
🎭 They copied others, rehearsed interactions or suppressed visible traits
🏫 Childhood provided routines and external structure that adult life no longer provides
📚 Strong language or academic ability hid difficulties in other areas
🎯 Their interests appeared culturally or age-typical
🤫 Distress appeared as quiet withdrawal rather than disruptive behaviour
🧩 Traits were attributed separately to shyness, anxiety, sensitivity or perfectionism
🌍 Clinicians, teachers or family relied on stereotypes based on a narrow group
📈 Adult work, relationships, independent living or parenting finally exceeded available capacity
Masking can make someone appear socially comfortable while they calculate responses, monitor body language, suppress movement and recover in private. It is not unique to autism, but it can hide autistic traits.
A late diagnosis is therefore not late-onset autism. It is a new explanation for a pattern that has usually been present throughout life.
Read more in Autism in High-Masking Adults and Late-Diagnosed Autism in Adults.
🔍 Autism, Overlap and Co-Occurring Conditions
No single autistic trait is exclusive to autism.
Sensory sensitivity can occur with ADHD, migraine or anxiety. Social withdrawal may reflect depression, trauma or social anxiety. Routines can be related to obsessive-compulsive disorder; deep interests can accompany giftedness or personality. Several explanations may coexist.
An assessment looks at the whole pattern and timeline, not just whether individual traits are relatable.
Autism can also coexist with:
🧠 ADHD
🌪️ Anxiety disorders
🌧️ Depression
🧱 Trauma-related conditions
🔁 Obsessive-compulsive disorder
🗣️ Language or learning differences
🧩 Intellectual disability
😴 Sleep problems
⚡ Epilepsy and other health conditions
Not every difficulty should be attributed to autism. An autistic person may still need treatment for depression, investigation of pain, ADHD support or trauma-informed care.
If attention, impulsivity and activation are also central, read Autism vs ADHD in Adults.
🧑⚕️ How Is Autism Diagnosed in Adults?
There is no single behaviour, questionnaire score or brief observation that can diagnose autism.
A comprehensive adult assessment usually considers:
🗓️ Early development and childhood characteristics
💬 Current communication and social experience
🔁 Routines, interests, movement and responses to change
🔊 Sensory differences
🏠 Daily functioning, support needs and environmental context
🎭 Masking and compensatory strategies
🩺 Mental health, physical health and possible alternative or additional explanations
A clinician may use structured interviews or observational tools. Childhood informants, school reports or other records can add context where available, but they are not substitutes for listening to the adult.
Online questionnaires can organize questions or support a decision to seek assessment. They cannot confirm or exclude autism.
Being articulate, making eye contact, having a career, maintaining a relationship or feeling empathy does not rule out autism. A careful assessment asks not only whether a person can do something, but how they do it, how reliably they can do it and what it costs.
Diagnosis can offer explanation, accommodations, legal recognition and targeted support. People without access to assessment can still use low-risk adjustments such as clearer communication, sensory changes, predictability and recovery time.
🛠️ What Actually Helps Autistic People?
The most useful support begins with the person’s actual profile rather than a generic idea of autism.
Helpful support may include:
🔊 Reducing avoidable sensory pain and overload
💬 Using clear language and allowing processing time
📅 Making expectations, plans and changes more predictable
🧠 Supporting planning, task initiation and daily living without shame
🤝 Respecting all valid forms of communication
🪫 Building in recovery before capacity collapses
🎯 Protecting access to meaningful interests and autistic community
🏠 Adapting home, education, healthcare and work environments
🩺 Identifying and treating co-occurring physical or mental-health conditions
🧭 Giving the autistic person meaningful control over goals and decisions
Support should not be judged only by whether the person looks less autistic. Forced eye contact, suppression of harmless stimming or training someone to tolerate preventable distress may improve outward conformity while increasing internal cost.
Learning new skills is not inherently harmful. The test is whether support improves communication, autonomy, safety, participation and quality of life—and whether the autistic person’s experience helps define success.
When overload does reduce access to speech, movement or thinking, Autistic Shutdowns in Adults explains the signs, triggers and recovery needs.
🚫 Common Myths About Autism
“Autistic people do not want relationships”
Many autistic people want closeness, friendship, partnership and community. They may prefer different forms, rhythms or levels of contact and may find conventional social maintenance exhausting or unclear.
“Autistic people lack empathy”
Empathy is not one ability. Someone may feel another person’s emotion intensely while needing explicit information to identify what happened or what response is wanted. Communication mismatch, delayed processing, alexithymia and overload can all affect how empathy is expressed.
“You cannot be autistic if you make eye contact”
Some autistic people naturally make eye contact. Others use it deliberately, tolerate it briefly or look at a nearby facial feature. The important question is not whether it happens, but how it is experienced and what processing cost it creates.
“Every autistic person is either intellectually disabled or a genius”
Autistic people have the full range of intellectual ability. Skills can also be uneven. Intelligence, spoken language and independent-living ability should never be treated as interchangeable.
“Autism looks the same in everyone”
The core pattern is shared, but its expression varies with language, intellectual profile, age, gender, culture, health, environment, learning history, masking and available support.
“Autism is only relevant in childhood”
Autistic children become autistic adults. Needs may change, and adults may develop better strategies, but autism does not expire at 18.
🌿 If You Are Wondering Whether You May Be Autistic
You do not need to decide everything immediately.
A useful first step is to look for patterns rather than collect isolated traits:
🗓️ What was present in childhood, even if it was interpreted differently?
🧩 Which experiences appear across communication, sensory processing, routines, interests and change?
🌍 How do they show up at home, at work, in relationships and when you are alone?
🎭 What do other people see, and what effort or recovery remains hidden?
🛠️ Which adjustments reliably make daily life more accessible?
Keep examples, not just labels. “Social situations are difficult” is broad. “I rehearse three versions of a phone call, monitor my face throughout it and need an hour alone afterward” gives more useful information.
Self-recognition can be meaningful where assessment is inaccessible. Stay open to overlap and other explanations. The goal is not to win a label, but to understand the pattern well enough to find appropriate support.
🪞 Reflection Questions
- Which parts of the autism pattern feel most relevant to your life: communication, sensory processing, predictability, focused attention, movement or something else?
- Which of these patterns can you trace back to childhood?
- Where is there the biggest difference between how capable you look and what functioning actually costs?
- Which environments make your autistic characteristics easier or harder to manage?
- What is one adjustment that would reduce unnecessary effort without asking you to become a different person?
🎯 Conclusion
Autism is a lifelong developmental pattern, not one narrow type of person. It can involve disability and strength, stable differences and changing capacity, visible support needs and invisible effort.
The overall pattern matters more than any single sign. So do the person’s internal experience, history, support needs and environment. No autistic person should be reduced to deficits, turned into an inspirational exception or forced into one story.
The most useful question is rarely “How autistic does this person look?”
It is: What is this person’s pattern, what is costing them, and what helps them access their life?
❓ Frequently Asked Questions
Is autism a mental illness?
No. Autism is a neurodevelopmental condition or difference, not a mental illness. Autistic people can also experience mental-health conditions such as anxiety, depression or trauma-related difficulties.
Can someone become autistic in adulthood?
Autism does not begin in adulthood. Some characteristics may become more visible when demands increase, support decreases, masking becomes unsustainable or burnout reduces previous coping capacity. The recognition or diagnosis can be new even though the developmental pattern is not.
Can autistic people be social and empathetic?
Yes. Autism can affect how social information is processed and how empathy is expressed, but it does not remove the desire or capacity for connection, care or emotional depth.
Can autism and ADHD occur together?
Yes. A person can meet the criteria for both autism and ADHD. The combination is often informally called AuDHD. Shared features can include sensory differences, intense focus, transition difficulties and executive-function challenges, while each condition also has distinct patterns.
Is Asperger’s still a diagnosis?
Asperger’s syndrome is no longer a separate diagnosis in the DSM-5 or ICD-11; it has been incorporated into the broader autism spectrum. Some people continue to use the term because it is part of their diagnosis, history or identity.
Can autism be cured?
Autism is lifelong and is not a disease that needs to be removed from the person. Support can improve communication, access, autonomy, safety and quality of life. Co-occurring conditions and specific sources of distress should still be identified and treated rather than dismissed as “just autism.”
Autism is a lifelong neurodevelopmental difference. Learn how it can shape communication, sensory processing, attention, routines and daily life.
📚 References
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📚 National Institute for Health and Care Excellence. (2021). Autism spectrum disorder in adults: diagnosis and management.
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📚 Lord, C., Charman, T., Havdahl, A., et al. (2022). The Lancet Commission on the future of care and clinical research in autism. The Lancet, 399(10321), 271–334.
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📚 Jones, D. R., Botha, M., Ackerman, R. A., King, K., & Sasson, N. J. (2024). Non-autistic observers both detect and demonstrate the double empathy problem. Autism, 28(8), 2053–2065.
📚 Strömberg, M., Liman, L., Bang, P., & Igelström, K. (2022). Experiences of sensory overload and communication barriers by autistic adults in health care settings. Autism in Adulthood, 4(1), 66–75.
📚 Lai, M.-C., Kassee, C., Besney, R., et al. (2019). Prevalence of co-occurring mental health diagnoses in the autism population: A systematic review and meta-analysis. The Lancet Psychiatry, 6(10), 819–829.
📚 Pukki, H., Bettin, J., Outlaw, A. G., et al. (2022). Autistic perspectives on the future of clinical autism research. Autism in Adulthood, 4(2), 93–101.
📚 Hviid, A., Hansen, J. V., Frisch, M., & Melbye, M. (2019). Measles, Mumps, Rubella Vaccination and Autism: A Nationwide Cohort Study. Annals of Internal Medicine, 170(8), 513–520.
📚 van Rooij, D., Anagnostou, E., Arango, C., et al. (2018). Cortical and Subcortical Brain Morphometry Differences Between Patients With Autism Spectrum Disorder and Healthy Individuals Across the Lifespan. American Journal of Psychiatry, 175(4), 359–369.
📚 Ilioska, I., Oldehinkel, M., Llera, A., et al. (2023). Connectome-wide Mega-analysis Reveals Robust Patterns of Atypical Functional Connectivity in Autism. Biological Psychiatry, 94(1), 29–39.
📚 Bourgeron, T. (2015). From the genetic architecture to synaptic plasticity in autism spectrum disorder. Nature Reviews Neuroscience, 16, 551–563.
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📚 Thomson, A. R., Pasanta, D., Arichi, T., & Puts, N. A. (2024). Neurometabolite differences in Autism as assessed with Magnetic Resonance Spectroscopy: A systematic review and meta-analysis. Neuroscience & Biobehavioral Reviews, 162, 105728.
📚 Green, S. A., Hernandez, L., Lawrence, K. E., et al. (2019). Distinct Patterns of Neural Habituation and Generalization in Children and Adolescents With Autism With Low and High Sensory Overresponsivity. American Journal of Psychiatry, 176(12), 1010–1020.
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